Asthma mediators

It has been known for some time that overweight or obese can increase the likelihood of developing certain chronic health problems like heart disease, diabetes, rheumatoid arthritis and certain cancers ago. Researchers have also observed that as the incidence of obesity is increasing in recent decades, so is the incidence of asthma and allergic diseases. Although this relationship could be coincidental, there are several factors that may indicate a possible association.

Overweight people have noted that increased gas capture his lungs and decreased inspiratory capacity as their body mass index (BMI) increases. These problems can lead to other respiratory problems that are not included asthma and sleep apnea Frequent respiratory infections. Esophogeal reflux, often referred to as heartburn, is more common, as is well known to be a trigger for many asthmatics.

Changes in eating habits in industrialized nations may also be a factor in the development of asthma. Researchers have found that certain fatty acids such as linoleic and eicosapentaenoic acid can reduce inflammatory mediators that are associated with asthma. Interestingly, the incidence of atopy, allergy or skin reactions, no increases in overweight individuals, meaning that some common allergic pathways involved in the development of asthma attacks are not a part of this inflammatory response.

Other assumptions that have been made are possible genetic factors and hormonal factors. It has been observed that the hormone leptin, which is produced by fat cells and found in highest concentrations in overweight, also has an effect on the inflammatory response and may influence asthma.

Although the relationship between obesity and asthma is not well understood, it is clear that losing weight can be just as if not more important than continually growing anti-inflammatory drugs in some individuals. Asthmatics may have special difficulty losing weight including the use of oral steroids are well known to cause weight gain. Often asthma symptoms are aggravated by increased activity, which can make it difficult to exercise. Asthmatics should consult with your doctor before starting any weight loss program. While losing weight is difficult, can dramatically improve an asthmatic health and ability to enjoy life!

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