Acne inflammation and Bacterial Infections

Acne generally is caused by a plurality of factors. In general, there are four major factors that cause acne: genetics, hormonal Acne inflammation bacteria, and inflammatory response.

Genetics is a factor as is well known that several members of the same family can be affected with moderate to severe acne scars.
Another causal component in acne is the presence of bacteria in the follicular canal. This is not great news, as an adult human being receives ten times more microbial cells as mammalian cells, and he (she) transport of about 1.25 kg of microbes. Moreover, it has been estimated that provide host for at least 1500 different microbial taxa have combined more than 200 times more genes than our own genome. Most of these agencies have not yet been studied in the laboratory, and therefore know very little about them.

Not only our innate micro flora protect us against external pathogens, but also provide us with as many as 10 of our energy needs, providing a range of vitamins, and play a key role in the development of our defense system and mucosal areas. But that’s another story, for innate microbes can also be harmful to us when they go out of balance.

Inside the follicular canal are bacteria that are indigenous to the follicular lining. Among anaerobic bacteria flora, gram positive bacterium called Proprionibacterium acnes are present. Interestingly, they are present in abundance in the pathologically affected sites. They are reduced during contramicrobiana oral therapy, and its absence in the skin of nonhuman animals is surprising especially because animals do not have acne vulgaris.

Hormones influence the onset of acne

As they reached the age of puberty the body begins to change in many different ways. These changes include more hormone secretion, and one result is stimulating sebum glands that create a lubricating fluid skin called sebum. Sebum opposes drying hair, prevent excessive loss of moisture from the skin surface, mcontraene soft skin, and inhibits the growth of certain microbes. Sebum glands reside under your hair follicles (400-800 glands per cm2 on the face, forehead and upper chest) and sebum from reaching the surface of your skin once through your skin pores clear.

The skin is made up of various tissues (epidermis, connective, muscular and nervous) and is one of the main organs of the body in terms of area (approximately 1.75 m2) and weight (approximately 5 kg. ) Has a variety of tasks . The main one is to protect the underlying tissues of microbes.

The epidermis is a keratinised stratified, squamous epithelium. Its density ranges from 0.5 to 3 mm. according to their location and, being the outer layer of our skin, it is obviously an important place colonization of microorganisms.

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